Labels:text | screenshot | black and white | black | document OCR: ral of the Aminoglutethimide interferes with sev synthesis, biosynthetic steps involved in steroid bi 18 -, 19- exerting its effects on the C20 -, C22 -, 11 3- ase. Since itand 21-hydroxylases, and also on aroma „,it is inhibits biosynthesis early in the pathwa ng the useful as a blocking agent when alleviat in the effects of excessive steroid production, a drome thattreatment of patients with Cushing's syr e action of has resulted from adrenal carcinoma. Th ul in the aminoglutethimide on aromatase is use treatment of breast cancer since it inhibi ever, it has peripheral formation of oestrogens; how more now been superseded for this purpose b selective aromatase inhibitors such as t cause the 4-hydroxyandrostenedione, which do no th problem of cortisol deficiency (as seen w aminoglutethimi ...
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